An anti-aging cream that might
save your life

Trienelle® takes on skin cancer and aging

Half of all new cancers are skin cancers. In fact, they're more common than cancers of any other organ. Over 1.3 million cases of basal cell and squamous cell skin cancer are expected to be diagnosed this year.1 Sobering isn't it? But now a powerful form of an old standby offers new hope.

The antioxidant advantage

Antioxidants like vitamin C and E have become very popular in skin products and for good reason. There's a wealth of research documenting their value in protecting the skin from sun damage.

Most skin cancer is caused by overexposure to the sun. The ultraviolet (UV) radiation generates an excessive number of superoxide radicals in exposed skin cells. These highly reactive molecules can, among other things, cause serious damage to your DNA. As a result of this, skin cells may begin to reproduce uncontrollably, leading to benign, precancerous, or malignant lesions on the skin.2 In short, sun exposure can lead to skin weathering,3 abnormal growths, and in serious cases, skin cancer.4

Antioxidants counteract this effect by coupling with the free radicals before they can harm the DNA. The effectiveness of antioxidants in protecting the skin against sun damage has been well documented. A double-blind placebo study held at the University of Munich found that combined antioxidants (vitamins C and E in the study) reduce the sunburn reaction‹stopping the skin damage before it degenerates to something more serious.5

The following year, University of Leiden researchers demonstrated that topically applied antioxidants can be used to prevent UV rays from damaging epidermal layers.

In a study carried out specifically on the antioxidant qualities of vitamin E, researchers concluded that it's an effective sunscreen and prevents the formation of DNA lesions that lead to skin cancer.7

Natural compound combats aging and cancer

One of our panelists, Dr. Randall Wilkinson, has developed a skin cream to help you win the war against skin cancer and aging. It's a combination of several elements‹all of which add up to one of the most powerful skin-care products on the market, both for its disease-fighting capabilities and for its ability to restore a youthful appearance to the skin.

Trienelle Daily Renewal Crème is designed to address both the issue of cellular damage that can lead to skin malignancies as well as the more cosmetic issue of premature aging and skin weathering. In doing so, it uses a very unique and scientifically supported combination of natural ingredients.

Trienelle harnesses the proven power of tocotrienols

While vitamin E is helpful in protecting the skin from UV damage, not all vitamin E is created equal. The key is to find the most effective form to carry out this all-important task. That's where tocotrienols come in. As we reported in last month's Memebers Alert (as well as the December 1997 issue), there are two primary forms of vitamin E: tocotrienol and the more common alpha-tocopherol. While alpha-tercopherols are used in face creams and the majority of nutritional supplements on the market, tocotrienols are actually far more potent‹up to 60 times more effective.8

Trienelle includes both tocotrienols and mixed tocopherols, to take advantage of the full range of both forms of vitamin E.

Recent studies have verified this, concluding that the physiological activities of tocotrienols make them superior to alpha-tocopherols and that its role in cancer prevention may have "significant clinical implications."9

Tocotrienols offers other distinct advantages over alpha-tocopherols and other antioxidant nutrients used in skin-care products. They're better absorbed and distributed in the superficial and deep skin layers.10 Unlike alpha-tocopherol, which is quickly depleted by UV exposure, tocotrienols remain in the skin at greater concentrations and even help to preserve the levels of tocopherols in the skin. Tocotrienols, when applied to the skin, also help to retain vitamin E, even after UV exposure.11

And, in addition to its antioxidant capacity, tocotrienols have another important role in derailing the cancer process at the cellular level. As described in the September 1998 Member's Alert, tocotrienols also regulate a key biochemical supply necessary for cell proliferation. To put it simply, tocotrienols help short-circuit the excess spreading of cells, even when DNA damage has occurred.

Recent studies have verified that the physiological activities of tocotrienols make them superior to alpha tocopherols and that its role in cancer preventionmay have "significant clinical implications."

Trienelle includes both tocotrienols and mixed tocopherols, to take advantage of the full range of both forms of vitamin E, incorporating a particularly potent concentration of tocotrienols (extracted from rice bran and palm oil) for maximum benefit. Trienelle is the only skin-care product that uses tocotrienols, while alpha-tocopherol crèmes are readily available.

A new technology for skin care

Trienelle uses a newly developed technology to deliver the maximum benefit to your skin. It's called the TololurTM Skin Nutrition Complex, and it features an advanced liposomal delivery system. Liposomes are tiny drop like particles 300 times smaller than cells, Encased by fat-soluble membranes made from the same material as actual cells, liposomes penetrate quickly and deeply through the waterproof outer layer of the skin. When the liposomes come into contact with the cells of the dermis, the nutrients contained inside are transferred via osmosis into the living cells.

Each Tocolur liposome contains both tocotrienols and tocopherols, In addition, the formulators have included applephenone‹a recently discovered super-potent antioxidant. Extracted from green apples, applephenone also protects cells against carcinogens and is a natural antihistamine (helping to block allergic reactions like hives).

Trienelle offers complete skin protection

Dr. Wilkinson's goal in creating Trienelle was to have a skin care product that provided "the very best protection against skin cancer, sun, and aging-related damage available anywhere. Period."

Although Trienelle is priced the same as other premium skin care products, no expense was spared in using the best materials. Dr. Ron DiSalvo, the crème's chief formulator, noted, "The quality of ingredients and the high potencies of cutting-edge and active ingredients make Trienelle probably the most expensive formula [to manufacture] that I've ever put together."

Trienelle should be massaged into clean skin once in the morning and once before bedtime. Care should be taken to cover those areas most susceptible to sun damage‹the face, the back of the neck, and the ears. There's no need to wear and additional moisturizer, as the crème has a highly emollient lotion base (featuring chlorella) that attracts and holds moisture in the skin.

Aspen Benefits Group and Trienelle skin care products are not affiliated with the Health Sciences Institute.

For more information about the Health Sciences Institute or to become a member, call 01959 578 300

Trienele's other ingredients build
a wall of protection

Melatonin heals damaged skin
Melatonin increases Trienelle's antioxidant and antiaging properties. In fact, topically applied melatonin has been shown to protect against sunburn and to heal skin already burned.12

Immunoprotective complex
Radiation from the sun can seriously suppress the cellular immune system of the skin, which is the body's largest immuno-protective organ. Skin care ingredients are now being developed and evaluated for their IPF value (immuno-protective factor). Similar to the widely used SPF, the IPF describes the ability of a substance to protect against immune suppression caused by UV radiation.

Trienelle uses reishi and versicolor mushroom extracts and HI-IG colostrums to shield against the immuno-suppression caused by UV radiation. See the December 1996 and January 1997 Members Alert for more information on these powerful compounds.

Alpha-hydroxy acid (AHA) is a powerful skin exfoliant
AHA has become one of the most popular and widely used skin-care ingredients, mostly for its ability to improve the look of mature and prematurely aging skin through its natural exfoliating qualities.13

By speeding the rate of turnover of dead skin cells on the surface of the skin, AHA reduces the appearance of fine lines and wrinkles by revealing the fresher layers beneath the surface, Trienelle includes multi-fruit hydroxy acids (from bilberry, maple, orange, and lemon) at a level that maximizes the therapeutic benefit and minimizes any possible sensitivity or irritation.